FR054
| 英文名 | FR054 | CAS號(hào) | 35954-65-5 |
| 產(chǎn)品編號(hào) | FSY0336 | 分子式 | C14H19NO8 |
| 產(chǎn)品分類 | 化合物與抑制劑 | 分子量 | 329.30256 |
| 純度 | ≥95.0% | 儲(chǔ)存條件 | -20°C |
產(chǎn)品簡(jiǎn)介
FR054 是 HBO 酶 PGM3 的抑制劑，具有明顯的抗乳腺癌活性。
| 生物活性 |
FR054 is an inhibitor of the HBP enzyme PGM3, with a remarkable anti-breast cancer effect. |
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| 體外研究 |
FR054 (0.5-1 mM, 24-48 h) induces an early proliferation arrest followed by a marked cell death increase in breast cancer cells and induces apoptosis. The effect of FR054 occurs through PGM3 inhibition instead of other off-target effects.
Cell Viability Assay
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| 體內(nèi)研究 |
FR054 (1000 mg/kg, ip) suppresses cancer growth in MDA-MB-231 xenograft mice.
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| 分子式 |
C14H19NO8
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| 分子量 |
329.30
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| CAS號(hào) |
35954-65-5
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| 運(yùn)輸條件 |
Room temperature in continental US; may vary elsewhere. |
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| 儲(chǔ)存方式 |
Please store the product under the recommended conditions in the Certificate of Analysis. |
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